An increasingly diverse set of approaches are under development with the aim of measuring biological rather than chronological age. Assessing the age-related burden of damage and dysfunction with sufficient accuracy would enable cost-effective ... [Continue Reading]
Reversine Increases Cell Plasticity, and Appears to Allow Some Cell Types to Escape Senescence
If I'm understanding the results presented here correctly, the reversine small molecule enables senescent cells to return to a more normal state of function, including replication, at least in muscle cells examined in cell culture. The researchers ... [Continue Reading]
Towards Ways to Encourage Cells to Degrade Greater Amounts of Tau Protein
Researchers here report on an investigation of mechanisms regulating the turnover of tau protein in brain cells. The hope is to find approaches that will more aggressively clear the tau aggregates found in neurodegenerative conditions via the usual ... [Continue Reading]